Approach to management depends on which grade is identified in each patient. A breakdown of the management guidelines is displayed below.
If Grade 2 diarrhoea persists longer than 48 hours or is intolerable:
If diarrhoea symptoms do not resolve to grade ≤1 within 14 days, despite optimal supportive care and treatment interruption:
The diarrhoea grade can be used to guide the management strategy.
Adapted from CTCAE version 3.3
ADL=activities of daily living, CTCAE=Common Terminology Criteria for Adverse Events
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